Genomic organization and classification of the bovine WC1 genes and expression by peripheral blood gamma delta T cells.

TitleGenomic organization and classification of the bovine WC1 genes and expression by peripheral blood gamma delta T cells.
Publication TypeJournal Article
Year of Publication2009
AuthorsHerzig, CTA, Baldwin, CL
JournalBMC genomics
Volume10
Pagination191
Date Published2009
AbstractWC1 co-receptors are group B scavenger receptor cysteine-rich molecules that are found exclusively on gammadeltaT cells and are thought to be encoded by a multi-gene family. Previous studies have shown gammadeltaT cells that respond to a particular stimulus have unique WC1 molecules expressed. Prior to the onset of the studies described here only one full-length WC1 nucleotide sequence was publicly available, though three WC1 molecules had been distinguished based on monoclonal antibody reactivity. Furthermore, the number of WC1 genes found in the bovine genome and their sequences had not yet been resolved.
Alternate JournalBMC Genomics