Leonid A. Pobezinsky
Leonid A. Pobezinsky, Ph.D.
Office phone: 413-545-2393
Email: lpobezinsky [at] umass [dot] edu
Office location: 427J ISB
661 North Pleasant Street
Amherst, MA 01003
Ph.D.: Cancer Research Center, Moscow, Russia, 2003
Experimental Immunology Branch, NCI/NIH
2012 - Best presentation of unpublished work award, ThymUS
2008 - Best poster award, first place, ThymUS
1997 - George Soros Best Student Award, Open Society Foundation
Non-coding RNAs in the immune system
Our laboratory is interested in the molecular mechanisms that control differentiation and transformation programs within an organism. The immune system constantly undergoes differentiation and is prone to malignant transformation providing an excellent model to study these programs. Thus, the focus of the laboratory is to identify key regulators of genes that are critical for normal function and for tumorigenesis of the immune system. Recently, non-coding RNAs, miRNAs, have been shown to control expression of many genes at the transcriptional and post-transcriptional levels. Specifically, we would like to understand the function of tumor suppressive and oncogenic miRNAs that are expressed in the immune cells.