Carlos M. Gradil

Carlos M. Gradil, DVM, MS, PhD, DACT

Extension Professor

Equine Studies Program Coordinator

Photo of Dr. Carlos Gradil

Office phone: 413-577-2214

Fax: 413-545-6326

Email: cgradil [at] vasci [dot] umass [dot] edu

Office location: 427Q ISB

Mailing address:

661 North Pleasant Street
University of Massachusetts
Amherst, MA. 01003

M.S./Ph.D.: University of Minnesota
DVM: University of Lisbon, Portugal
Postdoctoral Training:
University of Minnesota
University of Ottawa
Cornell University

Honors and other distinctions:
AID, Fulbright, NATO, Rockefeller Fellow
Phi Zeta, Kappa Chapter
Diplomate of the American College of Theriogenology


ANIMLSCI 445A - Equine Reproduction Lab
ANIMLSCI 421 - Wildlife Reproduction
ANIMLSCI 497A - Equine Diseases and Health Management
ANIMLSCI 521- Physiology of Reproduction


The Wildlife Reproduction course is a model for teaching basic concepts in comparative reproduction.  Lecture topics are open discussion, and are problem-based learning built on cases and experiences acquired in real life situations, visits and discussions.   The curriculum incorporates hands-on experiences/observations that will nurture an understanding of the natural habitat and wildlife.  We will discuss:  i) The use of reproductive technologies to refresh the gene pool of zoo animals. ii) How to restrain and conduct procedures with wildlife iii) Problems and policy associated with endangered species iv) Daily management in wildlife sanctuaries, game ranches and zoos v) Wildlife medicine based on problem solving scenarios. vi) Conflicts of wildlife and human populations vii) Fertility suppression and contraception viii) Career and training/job opportunities.


Intrauterine Devices (IUDs) used to modulate the Reproductive Cycle and as Contraceptives in Nonhuman Primates.

For example,  mares in estrus can behave in ways that can make handling difficult. Current methods to suppress estrus behavior during the breeding season, when most horse competitions takes place, include:  pharmacological treatments; glass marbles; and negative reinforcement. Hormone-free behavior regulators have significant advantages over other methods. We are working on a frameless self-assembling intrauterine device (SIUD) prototype that suppresses estrus behavior in mares.

Other activities

Founder in 1996 and present co-owner of cafereprod-L [at] cornell [dot] edu a mailing list in small animal reproduction. The list is subscribed by over 250 leading names in the field worldwide facilitating access to expert opinion and contacts to veterinary colleges and reproduction specialty practices around the world.

Summer Practicum

AnSci 298 Practicum, (1 cr )  Shadow Equine Veterinarian Dr. Carlos Gradil at the UMass Equine Reproduction Clinic for 2 weeks during the May 15, 2016 - July 15, 2016 time period.

The goal of the practicum is to provide participants with current knowledge of assisted reproduction in the modern equine industry. We will discuss principles and mechanisms of normal and abnormal aspects of equine reproduction and current approaches to reproductive care and management. Content includes: functional anatomy, reproductive life cycles and terminology, discussion of breeding management, common causes of infertility and assisted reproductive technologies i.e., ultrasound, semen processing etc.

Students must make arrangements with Dr. Gradil for the specific 2 week time period that they would like to participate in the internship. Registration for the Summer Practicum is through Career Services.


Please contact me to make an appointment cgradil [at] vasci [dot] umass [dot] edu

Pre-Vet and Animal Sciences Club




Coyne MJ, Cousin H, Loftus JP, Johnson PJ, Belknap JK, Gradil CM, Black SJ, Alfandari D.  2009.  Cloning and expression of ADAM-related metalloproteases in equine laminitis.. Veterinary immunology and immunopathology. 129(3-4):231-41.