Pobezinsky Lab Awarded $2.7M Grant

Any successful immune response depends on the proper maintenance and differentiation of the involved cells. Cytotoxic T cell-mediated immune response is often compromised during chronic infection and cancer. Our studies, proposed in this R01 grant, not only will investigate a novel mechanism that profoundly influences both the maintenance and the differentiation of Killer T cells but will also provide a rationale for developing new immunotherapies.