Lauren Le Page

Ph.D Candidate ABBS

ABBS Graduate Student

Pronouns: They/them


ISB 460

llepage [at] umass [dot] edu

Lauren is a PhD candidate in the Animal Biotechnology and Biomedical Science program at UMass. Lauren graduated from UMass Amherst in 2015 with a B.S. in Animal Science, Biotechnology concentration.

Lauren’s research in the Telfer lab focuses on the hybrid pattern recognition receptor (PRR) and co-receptor: Workshop Cluster 1 (WC1) which is expressed as a multigenic array on gamma-delta T-cells of swine and ruminants. gamma-delta T-cells function as a bridge between the innate and adaptive immune system and play a protective role against infectious agents (bacteria, fungi, viruses) as well as in cancer and autoimmunity. Defining the role of WC1-mediated activation of gamma-delta T-cells within these species will allow us to exploit these cells when designing next-generation vaccines against zoonotic diseases like Leptospirosis, and Bovine Tuberculosis as well as non-zoonotic diseases like Porcine Reproductive and Respiratory Syndrome Virus (PRRSV). Lauren’s project focuses extensively on defining the total number and structure of WC1 genes found in swine and evaluating pathogen binding potential of each one of these genes.