Alexandria Wells

Ph.D Candidate, MCB


ISB 470

acwells [at] umass [dot] edu

Alex earned her B.A. in Biology/ Chemistry from New College of Florida in Sarasota, Florida. Alex’s research interests include elucidating novel post-transcriptional regulatory pathways during complex cellular transformations. Her current work in the Pobezinsky lab is focused on understanding the post-transcriptional mechanisms responsible for regulating CD8 T-cell differentiation. Specifically, Alex is interested in characterizing the role non-coding RNA’s play in this differentiation program. Once in the periphery, CD8 T cells have the ability to differentiate into effector cytotoxic T lymphocytes that will directly combat infection, or memory CD8 T cells that will act as a first line of defense upon re-infection. By studying the role of non-coding RNA’s in regulating these differentiation lineages, scientists can ultimately manipulate these cells to become more effective defenses against viruses and tumors.