Using breast milk to assess breast cancer risk: the role of mass spectrometry-based proteomics.

TitleUsing breast milk to assess breast cancer risk: the role of mass spectrometry-based proteomics.
Publication TypeJournal Article
Year of Publication2014
AuthorsSchneider SS, Aslebagh R, Wetie ANG, Sturgeon SR, Darie CC, Arcaro KF
JournalAdv Exp Med Biol
Volume806
Pagination399-408
Date Published2014
ISSN0065-2598
Abstract

Although mammography and treatment advances have led to declines in breast cancer mortality in the United States, breast cancer remains a major cause of morbidity and mortality. Breast cancer in young women is associated with increased mortality and current methods of detecting breast cancers in this group of women have known limitations. Tools for accurately assessing personal breast cancer risk in young women are needed to identify those women who would benefit the most from earlier intervention. Proteomic analysis of breast milk could identify biomarkers of breast cancer risk and provide a tool for identifying women at increased risk. A preliminary analysis of milk from four women provides a proof of concept for using breast milk to assess breast cancer risk.

DOI10.1007/978-3-319-06068-2_19
Alternate JournalAdv. Exp. Med. Biol.
PubMed ID24952194