Chang's meaning of capacitation: A molecular perspective.

TitleChang's meaning of capacitation: A molecular perspective.
Publication TypeJournal Article
Year of Publication2016
AuthorsGervasi MG, Visconti PE
JournalMol Reprod Dev
Date Published2016 Jun 3
ISSN1098-2795
Abstract

Dr. Min Chue Chang’s contributions to the field of reproductive biology set the stage for the development of the contraceptive pill and in vitro fertilization. Throughout his publications, Dr. Chang was also able to transmit his view of the fertilization process in ways that organized research for newer generations of reproductive biologists. Particularly relevant for the achievement of in vitro fertilization in mammals was the discovery that the sperm required a period of residence in the female tract to become fertilization-competent; Dr. Chang and Dr. Austin, in Australia, independently reported this process, known as sperm capacitation. This review discusses Dr. Chang’s views on capacitation, and puts them in the context of recent advances in the understanding of the molecular basis of this process. This article is protected by copyright. All rights reserved.

DOI10.1002/mrd.22663
Alternate JournalMol. Reprod. Dev.
PubMed ID27256723