| Title | Breast cancer expression of YKL-40 correlates with tumour grade, poor differentiation, and other cancer markers. |
| Publication Type | Journal Article |
| Year of Publication | 2011 |
| Authors | Shao R, Cao QJ, Arenas RB, Bigelow C, Bentley B, Yan W |
| Journal | British journal of cancer |
| Volume | 105 |
| Issue | 8 |
| Pagination | 1203-9 |
| Date Published | 2011 Oct 11 |
| Abstract | Serum levels of a secreted glycoprotein YKL-40 are elevated in patients with a wide range of cancers including breast, colorectal, and ovarian cancers. Furthermore, these increased levels correlate with poorer survival of cancer patients, suggesting that serum levels of YKL-40 might be a prognostic biomarker. However, the tissue expression of YKL-40 and its relationship with clinical outcomes and other potential markers are poorly understood. |
| DOI | 10.1038/bjc.2011.347 |
| Alternate Journal | Br. J. Cancer |