Carlos M. Gradil

Carlos M. Gradil, DVM, MS, PhD, DACT

Extension Associate Professor

Equine Studies Program Coordinator

Photo of Dr. Carlos Gradil

Office phone: 413-577-2214

Fax: 413-545-6326

Email: cgradil [at] vasci [dot] umass [dot] edu

Office location: 427U ISB

Mailing address:

661 North Pleasant Street
University of Massachusetts
Amherst, MA. 01003

M.S./Ph.D.: University of Minnesota
DVM: University of Lisbon, Portugal
Postdoctoral Training:
University of Minnesota
University of Ottawa
Cornell University

Honors and other distinctions:
AID, Fulbright, NATO, Rockefeller Fellow
Phi Zeta, Kappa Chapter
Diplomate of the American College of Theriogenology

Classes: Equine Diseases, Parasites & Treatment; Equine Reproduction; Horse Management

Assisted reproductive technologies

My current research interests include determination of PLC zeta (PLCζ) concentration in sperm of dogs and equine and how it relates to fertility. Some cases of male infertility, especially those associated with normal sperm numbers and motility may be caused by decreased amounts of a factor(s) in the sperm responsible for inducing egg activation and initiation of embryo development. Less than optimal fertility may be also explained by decreased amounts of this protein in sperm. This putative factor is likely to be the recently identified PLCζ. We are securing specimens of infertile dogs and stallions that visit our services as has been recently published in: C. Gradil, S-Y. Yoon, J. Brown, C. He, P. Visconti, R. Fissore. 2006. PLCζ: a marker of fertility for stallions? Animal Reproduction Science 94:23-25.

Other activities

Founder in 1996 and present co-owner of cafereprod-L [at] cornell [dot] edu a mailing list in small animal reproduction. The list is subscribed by over 250 leading names in the field worldwide facilitating access to expert opinion and contacts to veterinary colleges and reproduction specialty practices around the world.

Coyne MJ, Cousin H, Loftus JP, Johnson PJ, Belknap JK, Gradil CM, Black SJ, Alfandari D.  2009.  Cloning and expression of ADAM-related metalloproteases in equine laminitis.. Veterinary immunology and immunopathology. 129(3-4):231-41.